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1996-03-09
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Document 0394
DOCN M9650394
TI Pregnancy rates among women infected with human immunodeficiency virus.
Adult/Adolescent HIV Spectrum of Disease Project Group.
DT 9605
AU Chu SY; Hanson DL; Jones JL; Division of HIV/AIDS Prevention, Centers
for Disease Control and; Prevention, Atlanta, Georgia, USA.
SO Obstet Gynecol. 1996 Feb;87(2):195-8. Unique Identifier : AIDSLINE
MED/96148892
AB OBJECTIVE: To examine pregnancy rates among women infected with human
immunodeficiency virus (HIV). METHODS: We used data from an ongoing
survey of medical records of 3915 women who were 15-44 years of age,
infected with HIV, and who received care between January 1990 and August
1994 in more than 90 clinics, hospitals, and private practices in 11
United States cities. RESULTS: At enrollment, 570 (14%) of these women
were pregnant. Pregnancy rates at entry varied significantly (P < .05)
by age in years (15-19 [47%], 20-24 [30%], 25-29 [18%]; 30-34 [11%];
35-39 [5%]; 40-44 [2%]); clinical status (with AIDS opportunistic
illness [3%], without AIDS opportunistic illness [17%]; and
race-ethnicity (white [12%], black [17%], Hispanic [8%], Asian [0%],
Native American [30%]) but not by mode of exposure (injecting drug use
[10%], heterosexual contact [15%], and blood transfusion [12%]). After
enrollment, 5.8% of women became pregnant each year. New pregnancies
were significantly less likely to occur among women with an AIDS
opportunistic illness (adjusted rate ratio 0.4, 95% confidence interval
[CI] 0.2-0.6), and significantly more likely to occur among women who
were less than 25 years of age (adjusted rate ratio 8.3, 95% CI
5.3-13.2) and who were black (adjusted rate ratio 1.6, 95% CI 1.2-2.1).
Among women who were pregnant at enrollment or during observation, 12%
were pregnant more than once. CONCLUSIONS: High rates of pregnancy at
entry to medical care among HIV-infected women stress the importance of
counseling and voluntary testing as routine obstetric-gynecologic
practice. In some groups, rates of new pregnancies remain high; standard
HIV care for women should include family planning services and assurance
that if a woman chooses to practice contraception, contraceptives will
be available and affordable.
DE Adolescence Adult Female Human HIV Infections/*EPIDEMIOLOGY
Pregnancy/*STATISTICS & NUMER DATA Pregnancy Complications,
Infectious/*EPIDEMIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).